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PSA testing in the “real world”… from 2010 to 2015
A newly published article in the journal Cancer suggests that, in fact, the USPSTF guidance on use of the PSA test for risk of prostate cancer has had little impact in the “real world” between 2010 and...
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Non-rising PSA but radiographic progression in men on treatment with...
A recent presentation at the European Society of Medical Oncology (ESMO) annual meeting in Copenhagen, Denmark, has suggested that some men on treatment with enzalutamide (Xtandi) may have radiographic...
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Of politics, prostate cancer, screening, and editorial opinions
We don’t often refer to articles in what are primarily political publications like The Hill, but an OpEd in that journal this week did catch our attention, and not in a particularly good way either. We...
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tPSA, cPSA, %fPSA and risk for diagnosis with and death from prostate cancer
Data from a series of > 1,200 Danish patients, all referred by their primary primary care physicians to a single, specialized urology practice, seems to confirm what has long been suspected about...
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Responsibilities unasked for and the role of the USPSTF
A commentary in this week’s issue of the New England Journal of Medicine provides some valuable, historical insight into how it was that the U.S. Preventive Services Task Force (USPSTF) ended up with...
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What you can’t prove can still be presented as if it were the truth
Another new article (this time in the journal JAMA Surgery) has tried to draw links between the USPSTF guidance on prostate cancer screening and a decrease in the numbers of men being referred to...
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So drinking cranberry juice can lower your PSA level, but what does that mean?
As we have noted numerous times before, there are all sorts of things that can be done to lower one’s PSA level, but knowing whether these effects are clinically meaningful is a very different issue....
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“The PSA clock” by Dr. Michael Glodé
Dr. Michael Glodé is a medical oncologist who practices in Colorado, and who has extensive experience in the management of prostate cancer. He also blogs on a regular basis at prost8blog. Your...
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USPSTF selects AUA-nominated urologist to review evidence report on prostate...
As many readers will be aware, the U.S. Preventive Services Task Force (USPSTF) is in process of developing a new “evidence report” which will form the basis of any update to current USPSTF...
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Risk, prostate cancer, and being 70 to 80 years of age
So a relatively new article in Reviews in Urology caught your Sitemaster’s eye this morning — and worried him because it seemed to be communicating a conclusion of questionable accuracy, which we will...
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Genetics, PSA, and steps toward a better prostate cancer risk management...
A new analysis of a large data set compiled by Kaiser Permanente suggests that combining PSA data with genetic risk data may offer a much more effective way to assess risk for clinically significant...
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Family history, PSA testing, and risk for diagnosis with prostate cancer
A presentation at the ongoing annual meeting of the European Association of Urology (EAU), in London, England, has reported (perhaps unsurprisingly) that PSA testing for risk of prostate cancer based...
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MRI as a means of screening for prostate cancer? Probably not!
A report on the HealthDay web site related to a presentation about the role of MRI scanning in the diagnosis of localized prostate cancer seems to demonstrate a significant division of views about the...
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USPSTF changes guidance on testing for risk of prostate cancer
As yet we have not seen the details, but, according to a report on National Public Radio early this morning, the US Preventive Services Task Force (USPSTF) has stated that men up to age 70 should...
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New draft USPSTF guidance on screening for risk of prostate cancer (the details)
As indicated earlier this morning, the US Preventive Services Task Force (USPSTF) has issued new draft guidance on screening for risk of prostate cancer. Access to all the relevant details is provided...
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PSA density vs. PSA level and the prediction of prostate cancer risk
A newly published study in the journal Urology (the “Gold Journal”) has suggested that — at least for patients with a PSA level between 4 and 10 ng/ml — PSA density may be better than PSA level in the...
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The evolution of evaluation of risk for clinically significant prostate cancer
Whatever one may happen to think about the value of the PSA test, we all know that it is very bad at actually telling a doctor or a patient if that patient is at real risk for clinically significant...
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Prostate cancer detection and associated risk management
Dr. Michael Barry has been a long-time advocate for caution in the appropriate use of PSA testing and for awareness of the risks of over-treatment of low-risk forms of prostate cancer. He is also a...
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Of CTCs, EMT, PSA, and megakaryocytes … Huh?
A newly published study in Clinical Cancer Research has implied the potential development of a completely new and much more accurate way to be able to identify risk for metastatic prostate cancer. The...
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An update on “screening” for prostate cancer: four perspectives
To quote the abstract of the paper discussed below, the use of the PSA test to screen for risk of prostate cancer “in men at normal risk of prostate cancer is one of the most contested issues in cancer...
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